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Ebook Cellular and Molecular Immunology

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Cellular and Molecular Immunology

Ebook Cellular and Molecular Immunology

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Review

"This is one of the premier textbooks of immunology. It covers all aspects of immunology from the innate immune response to adaptive immunity, and their role in antimicrobial defense, autoimmunity, allergy, etc." Reviewed by Luis Sigal, DVM, PhD (Thomas Jefferson University)

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About the Author

Abul K. Abbas, MBBS, Distinguished Professor and Chair, Department of Pathology, University of California San Francisco, San Francisco, California

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Product details

Paperback: 608 pages

Publisher: Elsevier; 9 edition (May 25, 2017)

Language: English

ISBN-10: 9780323479783

ISBN-13: 978-0323479783

ASIN: 0323479782

Product Dimensions:

8.5 x 1 x 11 inches

Shipping Weight: 3 pounds (View shipping rates and policies)

Average Customer Review:

4.7 out of 5 stars

19 customer reviews

Amazon Best Sellers Rank:

#45,234 in Books (See Top 100 in Books)

This is a very comprehensive presentation of the immune system. It covers it in a most up to date manner for example including the most recent studies on CAR-T cells and PD-1 inhibitors.It covers each of the immune elements in detail and that includes the innate and adaptive system. Specifically:1. The discussion of T helper cells is complete with an excellent summary and detail on each of its elements.2. The CTL are covered in equal detail and these are critical in the understanding of current immunotherapy.3. The complement system is covered but here I would have liked to see it more on a stand alone basis. The complement system gets limited coverage but recent work in AMD for adults seems to give it some potential.4. Immunotherapy in a broader sense is covered but not in detail. For example there is limited inclusion of dendritic cell therapy for prostate cancer.It is not clear what this is used for, since it is so encyclopedic. I have considered it akin to a "shop manual" for immunology. It has every part and piece and it details what part is connected to what other part.However, the Immune System is a system and this system view is lacking. To understand immune system failures one must understand the basic dynamics of the immune system. This book detailed every piece and part but lacks leaving the reader with an overall system view. One can walk away with encyclopedic knowledge but not necessarily with a visceral understanding of the workings.Not withstanding my critique, this is clearly the standard for such presentation. However theKuby Immunology series does add a dimension which is missing, namely the laboratory efforts involved in understanding where and how many of these facts were determined. I have used the Kuby books from the first addition forward and they are an excellent complement to this work. Also I have found the book by How the Immune System Works (The How it Works Series) is an excellent "road map" and system oriented book than can be used in conjunction with this one.Overall this book focuses primarily on the immune system elements. However there are many underlying genetic pathways that play a significant role and these are not considered in any detail. For example, the impact on the NF-kB pathway is significant as a promoter of cytokine production. I would assume that one should be aware of its function and impact.Overall this book is essential to have for anyone trying to do work in the current state of immunology. It provides the details and foundational elements that are invaluable. From this book one can jump quickly to the current literature.

I initially want to have the 8th edition of this book, and I found that there is a newest version as the 9th edition. I have compared this one with the last edition, and found that this new version really covers some intriguing and state-of-art concepts like immunotherapy for cancer (second generation CART, PD-L1), although the length is limited. Some of the basic concepts have been either rewritten or modified to match the main flow of immunological findings. It is a good book but only if you have a basic understanding of how immunity works. Otherwise, pls start with the guiding book like "how the immune system works" contributed by Sompayrac

So the material may be better cemented into my brain, I purchased the 9th edition and have begun reading it just after having completed reading the 8th edition. I bought the print book because reading about biology is just easier using a real book. The print edition comes with the full book in electronic form. Having both the print version and the electronic version is incredibly useful. For serious and un-distracted reading, the print edition cannot be beat. For review, searches, and reading while away from your "real" book, the electronic version is invaluable. I am also thankful that on the electronic version, we can highlight text and copy it. This makes creating flashcards and taking notes faster and easier. The content is detailed and clear. The recommendations for further reading at the end of each chapter are useful. This is my favorite immunology text book by far.

The "gold standard' for basic immunology.Have every edition back to the first one.Every practicing allergist-immunologist should have one.Makes it easier to understand the basic immunology of how mAbs work.

This is an indescribable accomplishment when it comes to presenting complex subject matter in a comprehensible manner! But I recommend reading the same authors' book, Basic Immunology: Functions And Disorders Of The Immune System before reading this one, if you do not have a background in immunology.

Abbas is the Best immunology text on the market -- excellent in all categories! Excellent text and excellent pictures to help understand the complex world of immunology. Great for beginning and advanced immunology students and colleagues that want to read the latest additions to the field.

Well written, explains concepts in the right order. The Student Consult is extremely useful.

the book is perfect and on-time delivery.

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Ebook Download Troublemaker: Surviving Hollywood and Scientology, by Leah Remini

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Troublemaker: Surviving Hollywood and Scientology, by Leah Remini

Ebook Download Troublemaker: Surviving Hollywood and Scientology, by Leah Remini

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Review

“An aggressively honest memoir . . . Troublemaker is the most raw and revealing Scientology memoir to date.”—Entertainment Weekly   “Leah’s story is a juicy, inside-Hollywood read, but it’s more than that. It’s a moving story about the value of questioning authority and how one woman survived a profound crisis of faith.”—People   “Remini [offers] up some juicy tidbits from her decades in the church.”—Newsweek

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About the Author

Leah Remini is an actor, producer, and writer. A fixture on television since the age of eighteen, Remini is best known for her beloved role of Carrie on the nine-season hit The King of Queens. Remini went on to produce and star in one of the earliest and most successful comedic web series, In the Motherhood, and appeared in the movie Old School alongside Will Ferrell and Vince Vaughn. In 2010, Remini helped launch and co-hosted the first season of the CBS daytime hit show The Talk, and in 2013 she was seen on the dance floor in Dancing with the Stars. She currently co-stars in the TV Land comedy The Exes and TLC’s reality show Leah Remini: It’s All Relative, which she also created and executive produces. Remini finds great joy in her philanthropic work with numerous and diverse military, women’s, and children’s charities. She lives in Los Angeles with her husband and daughter.

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Product details

Hardcover: 256 pages

Publisher: Ballantine Books; First Edition / First Printing edition (November 3, 2015)

Language: English

ISBN-10: 110188696X

ISBN-13: 978-1101886960

Product Dimensions:

6.4 x 1.1 x 9.5 inches

Shipping Weight: 1.2 pounds (View shipping rates and policies)

Average Customer Review:

4.7 out of 5 stars

5,019 customer reviews

Amazon Best Sellers Rank:

#51,296 in Books (See Top 100 in Books)

An avid 'King of Queens' fan and Leah handling Twitter after 'The Talk' debacle, add a sheer curiosity about Scientology, this book was the answer!Leah, in complete generosity, gives us an intimate look into her family and Scientology.She begins in her early childhood. If you, like me, have tried wrapping your mind around anyone choosing to jump into Scientology, you will finally gain insight! She explains Scientology so generously even after everything she went through. She gives the details of classes, procedures and orders very succinctly. She describes, eloquently, the people involved in the beginning to the bitter end. Yet doesn't have a tone of hate or bitterness. Quite a feat!The surprise for me was her detailed, funny and poignant stories about agents, auditions and jobs she's had. She's brutally honest....even about herself. She openly discusses other celebrities and it is a treat!It's open and honest. I'd dare say even if you don't adore Leah, if you want a look into showbiz and what it takes to make it...you will enjoy. If you want a detailed look into Scientology.....you will enjoy. If you just like learning more about different celebrities...you will enjoy. Regardless, you will enjoy and I dare say, come away with a respect for Leah and an admiration.

It's 7:20 AM as I write this, and I haven't slept since I started reading this book, moments after downloading it. I'm about 80% done at this point, but had to stop and post this early review (I'll update this a bit when I'm 100% done). I've never been much of a fan of sitcoms, so I'm not exactly part of the audience who has had much experience with Leah's acting work - although I knew who she was, certainly. I'd seen enough however to know I found her appealing and incredibly attractive long before I learned she'd be writing this just from what I'd seen in an episode of two of King of Queens. When I heard advance word of the release, having read just about every book there is on the subject of Scientology (from Inside Scientology, to Bare Faced Messiah, to Beyond Belief to The Unbreakable Miss Lovely), from personal accounts to journalistic exposes, I eagerly anticipated Troublemaker. The biggest surprise for me, first off, is how supremely readable "Troublemaker" is - how entertaining, honest, unpretentious, shocking and just plain funny it is. Leah has a big mouth, and she knows it, but her writing speaks directly to the reader in an open and unfiltered way that books written by celebrities rarely do. She isn't a bulls***ter, and she's not going to sugarcoat anything, including her herself. She even starts with something of a confession of past perceived sins, as she is all to aware that Scientology will strike at her as they are known to do, by using information gleaned from auditing to embarrass, intimidate and discredit. She knows she is now "fair game." Even with the little that I knew about her, her account of her early years with her family and struggles as an actress are highly entertaining, and make an honest impression that makes you feel more like a confidant than a reader. For this type of book, it is, surprisingly, very well written - free of fanciful prose, but deeply engaging, concise and highly personal. The early biographical chapters are vital, as it turns out, as it sets a very clear stage for why she was bound to one day become a monumental thorn in the side of Scientology. A theme that pops up a few times is how Leah was sometimes perceived as "lacking in class" (code sometimes used to discredit or embarrass truth tellers, female ones in particular) in comparison to the norm of perceived celebrities and society's elite. This book shows, clearly, that she has more class than the majority of Hollywood's elite put together. I can't wait to read the remaining 20%, and regardless of my ignorance of her acting career, with this book she's become one of my favorite people. If only more people in the world had the guts that Leah clearly has. More so than even the recent Going Clear documentary, this book, in my opinion, has the potential to expose Scientology for the abusive, draining, exploitative, paranoid and disingenuous organization that it has become, the Church of Cruise and Miscavige. And if you're looking for a real window into the bizarre, rarefied world of celebrity scientologists (Leah attending Tom Cruise's wedding to Katie Holmes, for example, and the subsequent fallout after she is brazenly manipulated to get J Lo and Marc Anthony to attend as well, is jaw dropping) you need look no further. Highly, highly recommended.

I admit, I haven’t really watched a lot of stuff with Leah Remini, I’m familiar with her from King of Queens, but that is about it. My mother has indicated that she has been on a lot of the talk shows lately talking about this book. I picked it up mostly for the insight into Scientology. I was not disappointed, but in the process of learning a bit more about scientology, there were some really interesting insights into her childhood, as well as her experiences getting into show businesses.This is a very quick read and it starts off right away by jumping into the issue of Scientology, so, if that is the reason why you are picking up the book, I recommend it for that aspect. I think that it is also useful to get the perspective of someone who is brought into Scientology through their family and it discusses how the appeal of the organization somewhat lured her mother into the organization and kept her persisting in it as an adult. It’s actually a really good insight/manual into understanding psychological aspect of cults, even if it is unintentional, it provides a personal aspect to one’s reflection on the process.It actually kind of highlights an abusive relationship with the organization, one in which a person stays even when it’s clear it might not be the healthiest relationship. Think riding a boat to the middle of nowhere and getting dumped in the water. However, these things are told in personal narratives, which Leah at no point is trying to label or, but just tell a story. At the same time, there are a lot of rewards that are highlighted for being a member of Scientology, especially in terms of networking within the Hollywood circles.It is also interesting to see how the fall-out and consequences for breaking with the church comes to light, in particular, Leah outlines her own humanity, pointing out areas in her life where she has messed up at the very start of the book, essentially expected to get sued by Scientology. In reading about the processes of other people and herself, there seems to be a strong leaning towards lawsuits by Scientology (which, many are aware of). Leah mostly keeps the story within the framework of her time directly in Scientology, with the final 10% (Kindle version) highlighting her time outside of the church and just how emotionally and socially devastating it was to her initially.Great read. Especially for those who are interested in Scientology. I think that the detail and first person account does a good job of at least tying it down to one person and their personal experiences.

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Troublemaker: Surviving Hollywood and Scientology, by Leah Remini PDF

Troublemaker: Surviving Hollywood and Scientology, by Leah Remini PDF